Single vs. double drain in modified radical mastectomy: A randomized controlled trial

Objective: It was aimed to test the hypothesis that use of a double drain results in less seroma formation, duration hospital stay, surgical site infection (SSI), postoperative pain, hematoma, flap necrosis compared single patients undergoing modified radical mastectomy. Material and Methods: This parallel-group, single-institution randomized controlled trial conducted at department surgery our institute between April 2015 July 2018. Women mastectomy were randomly allocated either (n= 98) or 98). Results: Both groups comparable for baseline variables such as age, co-morbidity, BMI, tumor characteristics. The yielded no better outcomes with estimated blood loss (101.67 ± 25.14 vs.101.67 24.40, p> 0.001), volume (898.81 116.42 vs 803.97 103.22 mL, minutes (103.19 15.96, 103.19 15.93) formation (13.4% 6.1%, p= 0.082). However, pain (mean 2.5 0.70 5.22 5.10, p< 0.000). On multivariable Cox regression analysis, associated lower risk significant [adjusted relative 0.14 (95% confidence interval (CI) 0.070-0.25)] overall complications 0.47, CI 0.26-0.86)]. multiple linear regression, drains group 0.01 days than (r2= 0.00, b= 0.388, 0.001). Conclusion: significantly reduces discomfort while demonstrating similar morbidity patient two drains. We thus recommend preferential (NCT02411617).